ELM - instance LIG_CORNRBOX in sequence O75376 at position 2051

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI000751	O75376 NCOR1 NCOR1_HUMAN	2051	2059	HRLITLADHICQIITQDFAR	TP	3N00	Homo sapiens (Human)	2440

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0114	x-ray crystallography	in vitro	Phelan,2010	support	certain	InteractionDetection FeatureDetection
not annotated		not specified		Xu,2002	not specified	not specified

Switches

This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

SWTI000246:

Binding of the 15367" target="_blank">all-trans-retinoic acid ligand to the nuclear Retinoic acid receptor alpha (RARA) makes the binding site for the CORNRBOX motif of Nuclear receptor corepressor 1 (NCOR1) inaccessible.

Pathways

KEGG: The sequence O75376 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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