The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003193 Q7Z6Z7 HUWE1
1972 1988 VMTQEVGQLLQDMGDDVYQQ TP --- Homo sapiens (Human) 4374

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro Zhong,2005 support certain ParticipantIdentification FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Zhong,2005 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Zhong,2005 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07820) MCL1_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
213 312 [mitab][xml]

o  Pathways

KEGG: The sequence Q7Z6Z7 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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