The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003185 Q14457 BECN1
BECN1_HUMAN
108 124 GTMENLSRRLKVTGDLFDIM TP 2P1L  
Homo sapiens (Human) 450

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0071 molecular sieving in vivo/in vitro Oberstein,2007 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Oberstein,2007 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Oberstein,2007 support certain InteractionDetection
experimental MI:0059 gst pull down in vivo/in vitro Oberstein,2007 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Oberstein,2007 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07817) B2CL1_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
90 188 2.3/2.3 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org