The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003186 O54918-2 Bcl2l11
B2L11_MOUSE
86 102 RPEIRIAQELRRIGDEFNET TP 1PQ1  
Mus musculus (House mouse) 140

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Chen,2005 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Chen,2005 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Chen,2005 support certain InteractionDetection
experimental MI:0968 biosensor Chen,2005 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Liu,2003 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07817) B2CL1_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
90 188 0.0008/0.0008 [mitab][xml]
(Q64373) B2CL1_MOUSE PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
90 188 [mitab][xml]
(P10415) BCL2_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
97 195 0.0045/0.0045 [mitab][xml]
(P97287) MCL1_MOUSE PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
194 293 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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