ELM - instance LIG_Actin_WH2_1 in sequence Q9U1K1 at position 464

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001662	Q9U1K1 spir SPIR_DROME	464	480	PREQLMESIRKGKELKQITP	TP	3MN5 3MN7	Drosophila melanogaster (Fruit fly)	1020

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0521	his tag	in vivo/in vitro/in silico	Quinlan,2005	support	certain
experimental	MI:0074	mutation analysis	in vivo/in vitro	Wellington,1999	support	certain	FeatureDetection
experimental	MI:0101	sequence based prediction	in silico	Wellington,1999	support	certain	InteractionDetection
experimental	MI:0004	affinity chromatography technology	in vivo/in vitro	Quinlan,2005	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Quinlan,2005	support	certain	FeatureDetection
experimental	MI:0040	electron microscopy	in vivo/in vitro	Quinlan,2005	support	certain	InteractionDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Quinlan,2005	support	certain	FeatureDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Ducka,2010	support	certain	InteractionDetection FeatureDetection
experimental	MI:0017	classical fluorescence spectroscopy	in vitro	Ducka,2010	support	certain	InteractionDetection
experimental	MI:0105	structure based prediction	in silico	Ducka,2010	support	certain	InteractionDetection
experimental	MI:0071	molecular sieving	in vivo/in vitro	Ducka,2010	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Notes
(P02578) ACT1_ACACA	PF00022 (Actin) Actin	2	375	[mitab][xml]
(P10987) ACT1_DROME	PF00022 (Actin) Actin	3	376	[mitab][xml]
(P68139) ACTS_CHICK	PF00022 (Actin) Actin	4	377	[mitab][xml]
(P68135) ACTS_RABIT	PF00022 (Actin) Actin	4	377	[mitab][xml]

Pathways

KEGG: The sequence Q9U1K1 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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