The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001662 Q9U1K1 spir
SPIR_DROME
464 480 PREQLMESIRKGKELKQITP TP 3MN5  
pdb:3MN5 3MN7  
pdb:3MN7
Drosophila melanogaster (Fruit fly) 1020

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0521 his tag in vivo/in vitro/in silico Quinlan,2005 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Wellington,1999 support certain FeatureDetection
experimental MI:0101 sequence based prediction in silico Wellington,1999 support certain InteractionDetection
experimental MI:0004 affinity chromatography technology in vivo/in vitro Quinlan,2005 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Quinlan,2005 support certain FeatureDetection
experimental MI:0040 electron microscopy in vivo/in vitro Quinlan,2005 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Quinlan,2005 support certain FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Ducka,2010 support certain InteractionDetection FeatureDetection
experimental MI:0017 classical fluorescence spectroscopy in vitro Ducka,2010 support certain InteractionDetection
experimental MI:0105 structure based prediction in silico Ducka,2010 support certain InteractionDetection
experimental MI:0071 molecular sieving in vivo/in vitro Ducka,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P02578) ACT1_ACACA PF00022 (Actin)
Actin
2 375 [mitab][xml]
(P10987) ACT1_DROME PF00022 (Actin)
Actin
3 376 [mitab][xml]
(P68139) ACTS_CHICK PF00022 (Actin)
Actin
4 377 [mitab][xml]
(P68135) ACTS_RABIT PF00022 (Actin)
Actin
4 377 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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