The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001663 Q92558 WASF1
WASF1_HUMAN
498 514 ARSVLLEAIRKGIQLRKVEE TP --- Homo sapiens (Human) 559

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Marchand,2001 support certain FeatureDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0016 circular dichroism in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Kelly,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kelly,2006 support certain FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Kelly,2006 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P02578) ACT1_ACACA PF00022 (Actin)
Actin
2 375 2.6/3.6 [mitab][xml]
(P68135) ACTS_RABIT PF00022 (Actin)
Actin
4 377 0.1/0.1 [mitab][xml]

o  Pathways

KEGG: The sequence Q92558 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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