The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001660 P42768 WAS
WASP_HUMAN
431 447 GRGALLDQIRQGIQLNKTPG TP 2A3Z  
pdb:2A3Z
Homo sapiens (Human) 502

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Marchand,2001 support certain FeatureDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0016 circular dichroism in vitro Marchand,2001 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Chereau,2005 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Chereau,2005 support certain InteractionDetection
experimental MI:0105 structure based prediction in silico Chereau,2005 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Chereau,2005 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P68135) ACTS_RABIT PF00022 (Actin)
Actin
4 377 0.6/0.6 [mitab][xml]

o  Pathways

KEGG: The sequence P42768 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org