ELM - instance LIG_Actin_WH2_1 in sequence O43516 at position 33

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001659	O43516 WIPF1 WIPF1_HUMAN	33	49	GRNALLSDISKGKKLKKTVT	TP	2A41	Homo sapiens (Human)	503

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0114	x-ray crystallography	in vitro	Chereau,2005	support	certain	InteractionDetection FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Chereau,2005	support	certain	InteractionDetection
experimental	MI:0105	structure based prediction	in silico	Chereau,2005	support	certain	InteractionDetection
experimental	MI:0101	sequence based prediction	in silico	Chereau,2005	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P68135) ACTS_RABIT	PF00022 (Actin) Actin	4	377	0.15/0.17	[mitab][xml]

Pathways

KEGG: The sequence O43516 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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