The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001659 O43516 WIPF1
WIPF1_HUMAN
33 49 GRNALLSDISKGKKLKKTVT TP 2A41  
pdb:2A41
Homo sapiens (Human) 503

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Chereau,2005 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Chereau,2005 support certain InteractionDetection
experimental MI:0105 structure based prediction in silico Chereau,2005 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Chereau,2005 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P68135) ACTS_RABIT PF00022 (Actin)
Actin
4 377 0.15/0.17 [mitab][xml]

o  Pathways

KEGG: The sequence O43516 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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