The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004173 Q91YR1 Twf1
TWF1_MOUSE
323 333 HKQSFAKPKGPAGKRGIRRL TP 7DS2  
Mus musculus (House mouse) 350

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0403 colocalization in vitro Johnston,2018 support certain
experimental MI:0944 mass spectrometry study of hydrogen/deuterium exchange in vivo/in vitro Johnston,2018 support certain InteractionDetection
experimental MI:0033 deletion analysis Johnston,2018 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Johnston,2018 support certain InteractionDetection
experimental MI:1088 phenotype-based detection assay Johnston,2018 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Johnston,2018 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Johnston,2018 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Takeda,2021 support certain InteractionDetection FeatureDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Hakala,2021 support certain
experimental MI:0788 knock out in vivo Hakala,2021 support certain
experimental MI:1088 phenotype-based detection assay Hakala,2021 support certain InteractionDetection
experimental MI:0033 deletion analysis Hakala,2018 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Hakala,2018 support certain FeatureDetection
experimental MI:1247 microscale thermophoresis in vitro Hakala,2018 support certain InteractionDetection
experimental MI:0826 x ray scattering Falck,2004 support certain InteractionDetection
experimental MI:0033 deletion analysis Falck,2004 support certain FeatureDetection
experimental MI:0404 comigration in non denaturing gel electrophoresis in vivo Falck,2004 support certain InteractionDetection
experimental MI:0113 western blot in vitro Vartiainen,2003 support certain ParticipantIdentification FeatureDetection
experimental MI:0404 comigration in non denaturing gel electrophoresis in vivo Vartiainen,2003 support certain InteractionDetection
experimental MI:0404 comigration in non denaturing gel electrophoresis in vivo Vartiainen,2003 support likely InteractionDetection
experimental MI:0404 comigration in non denaturing gel electrophoresis in vivo Palmgren,2001 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P14315) CAPZB_CHICK PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.051/0.053 [mitab][xml]
(P13127) CAZA1_CHICK PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P47753) CAZA1_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org