The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004164 Q9Y4E1 WASHC2C
WAC2C_HUMAN
1003 1020 TLHSANKSRVKMRGKRRPQT TP --- Homo sapiens (Human) 1320

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0045 experimental interaction detection McConnell,2020 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Edwards,2015 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Edwards,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47754) CAZA2_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q5RKN9) Q5RKN9_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q923G3) Q923G3_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.0077/0.0093 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y4E1 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org