The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004159 Q96B97 SH3KBP1
SH3K1_HUMAN
476 494 LSHPTTSRPKATGRRPPSQS TP --- Homo sapiens (Human) 665

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0045 experimental interaction detection McConnell,2020 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro McConnell,2020 support certain InteractionDetection
experimental MI:0045 experimental interaction detection Hernandez-Valladares,2010 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Hutchings,2003 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P14315) CAPZB_CHICK PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47756) CAPZB_HUMAN PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P13127) CAZA1_CHICK PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P52907) CAZA1_HUMAN PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q5RKN9) Q5RKN9_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(Q923G3) Q923G3_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.057/0.061 [mitab][xml]

o  Pathways

KEGG: The sequence Q96B97 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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