The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004165 Q6F5E8 CARMIL2
CARL2_HUMAN
1016 1037 LRHPTRARPRPRRQHHHRPPPG TP --- Homo sapiens (Human) 1435

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Edwards,2015 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Edwards,2015 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Lanier,2015 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lanier,2015 support certain FeatureDetection
experimental MI:0045 experimental interaction detection Lanier,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P47756) CAPZB_HUMAN PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 0.0025/0.0033 [mitab][xml]
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P52907) CAZA1_HUMAN PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P47754) CAZA2_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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