The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004163 Q6EDY6 Carmil1
CARL1_MOUSE
986 1003 RLEHFTKLRPKRNKKQQPTQ TP 3AA0  
Mus musculus (House mouse) 1374

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0403 colocalization in vitro Yang,2005 support certain
experimental MI:0045 experimental interaction detection Yang,2005 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Yang,2005 support certain FeatureDetection
experimental MI:0033 deletion analysis Yang,2005 support certain FeatureDetection
experimental MI:1088 phenotype-based detection assay Yang,2005 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Yang,2005 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Yang,2005 support certain
experimental MI:0405 competition binding in vitro Takeda,2010 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Takeda,2010 support certain InteractionDetection FeatureDetection
experimental MI:0519 glutathione s tranferase tag in vitro Takeda,2010 support certain
experimental MI:0045 experimental interaction detection Takeda,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Takeda,2010 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Takeda,2010 support certain InteractionDetection FeatureDetection
experimental MI:0405 competition binding in vitro Bruck,2006 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P14315) CAPZB_CHICK PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 4.0/4.0 [mitab][xml]
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P13127) CAZA1_CHICK PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P47754) CAZA2_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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