The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004167 Q641Q2 WASHC2A
WAC2A_HUMAN
1024 1041 TLHSANKSRVKMRGKRRPQT TP --- Homo sapiens (Human) 1341

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0045 experimental interaction detection Jia,2010 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Jia,2010 support certain
experimental MI:0096 pull down in vivo/in vitro Jia,2010 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Jia,2010 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Jia,2010 support certain InteractionDetection
experimental MI:0045 experimental interaction detection Hernandez-Valladares,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P14315) CAPZB_CHICK PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47756) CAPZB_HUMAN PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P47757) CAPZB_MOUSE PF01115 (F_actin_cap_B)
F-actin capping protein, beta subunit
6 240 [mitab][xml]
(P13127) CAZA1_CHICK PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P52907) CAZA1_HUMAN PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]
(P47754) CAZA2_MOUSE PF01267 (F-actin_cap_A)
F-actin capping protein alpha subunit
17 282 [mitab][xml]

o  Pathways

KEGG: The sequence Q641Q2 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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