The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003267 O43683 BUB1
BUB1_HUMAN
527 532 ISSLSSAFHVFEDGNKENYG TP --- Homo sapiens (Human) 1085

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Di Fiore,2015 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Di Fiore,2015 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Di Fiore,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q12834) CDC20_HUMAN PF00400 (WD40)
WD domain, G-beta repeat
[mitab][xml]

o  Pathways

KEGG: The sequence O43683 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org