The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002952 P48382 RFX5
RFX5_HUMAN
173 180 KTLVSMPPLPGLDLKGSESP TP 3V30  
Homo sapiens (Human) 616

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Xu,2012 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Xu,2012 support certain InteractionDetection FeatureDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Nie,2015 support certain InteractionDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Nie,2015 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Xu,2012 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9H9E1) ANRA2_HUMAN SM00248 (ANK)
ankyrin repeats
181 210 91.0/145.0 [mitab][xml]
(O14593) RFXK_HUMAN PF00023 (Ank)
Ankyrin repeat
123 155 140.0/228.0 [mitab][xml]
(O14593) RFXK_HUMAN SM00248 (ANK)
ankyrin repeats
123 152 140.0/228.0 [mitab][xml]

o  Pathways

KEGG: The sequence P48382 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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