ELM - instance DOC_WW_Pin1_4 in sequence Q8QGV2 at position 183

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002021	Q8QGV2 wee1-b WEE1B_XENLA	183	188	STPQVNINPFTPDSLEIQSS	TP	---	Xenopus laevis (African clawed frog)	595

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Okamoto,2007	support	certain
experimental	MI:0113	western blot	in vitro	Okamoto,2007	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Okamoto,2007	support	certain	FeatureDetection

Switches

This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

SWTI000170:

Phosphorylation of T186 in the Pin1-binding motif of Wee1-like protein kinase 1-B (wee1-b) induces binding to the pin1 protein.

Pathways

KEGG: The sequence Q8QGV2 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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