The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002007 Q8CFN5 Mef2c
MEF2C_MOUSE
107 112 DPDADDSVGHSPESEDKYRK TP --- Mus musculus (House mouse) 474

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Magli,2010 support certain
experimental MI:0434 phosphatase assay in vitro Magli,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Magli,2010 support certain FeatureDetection
experimental MI:0113 western blot in vitro Magli,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Magli,2010 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Magli,2010 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9QUR7) PIN1_MOUSE PF00397 (WW)
WW domain
7 37 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q8CFN5 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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