The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002010 Q3U182 Crtc2
CRTC2_MOUSE
133 138 DSSPYSPAYLSPPPESGWRR TP --- Mus musculus (House mouse) 692

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Nakatsu,2010 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Nakatsu,2010 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Nakatsu,2010 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q13526) PIN1_HUMAN PF00397 (WW)
WW domain
7 37 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q3U182 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org