Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001961 | Q04206 RELA TF65_HUMAN |
251 | 256 | VHRQVAIVFRTPPYADPSLQ | TP | --- | Homo sapiens (Human) | 551 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Ryo,2003 | support | certain | |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Ryo,2003 | support | certain | InteractionDetection |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Ryo,2003 | support | certain | FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000073:
Phosphorylation of T254 in the Pin1-binding motif of Transcription factor p65 (RELA) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Pathways
KEGG: The sequence Q04206 is implicated in the following 75 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Alzheimer disease
- Amoebiasis
- Antifolate resistance
- Apoptosis
- B cell receptor signaling pathway
- C type lectin receptor signaling pathway
- Cellular senescence
- Chagas disease
- Chemical carcinogenesis reactive oxygen species
- Chemical carcinogenesis receptor activation
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Cocaine addiction
- Coronavirus disease COVID 19
- Cytosolic DNA sensing pathway
- Diabetic cardiomyopathy
- Epithelial cell signaling in Helicobacter pylori infection
- Epstein Barr virus infection
- Fluid shear stress and atherosclerosis
- HIF 1 signaling pathway
- Hepatitis B
- Hepatitis C
- Herpes simplex virus 1 infection
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- IL 17 signaling pathway
- Inflammatory bowel disease
- Influenza A
- Insulin resistance
- Kaposi sarcoma associated herpesvirus infection
- Legionellosis
- Leishmaniasis
- Lipid and atherosclerosis
- Longevity regulating pathway
- MAPK signaling pathway
- Measles
- Mitophagy animal
- NF kappa B signaling pathway
- NOD like receptor signaling pathway
- Neurotrophin signaling pathway
- Neutrophil extracellular trap formation
- Non alcoholic fatty liver disease
- Osteoclast differentiation
- PD L1 expression and PD 1 checkpoint pathway in cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Pertussis
- Prolactin signaling pathway
- Prostate cancer
- RIG I like receptor signaling pathway
- Ras signaling pathway
- Relaxin signaling pathway
- Salmonella infection
- Shigellosis
- Small cell lung cancer
- Sphingolipid signaling pathway
- T cell receptor signaling pathway
- TNF signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Toll like receptor signaling pathway
- Toxoplasmosis
- Transcriptional misregulation in cancer
- Tuberculosis
- Viral carcinogenesis
- Yersinia infection
- cAMP signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement