The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001993 P84022 SMAD3
SMAD3_HUMAN
205 210 HSMDAGSPNLSPNPMSPAHN TP --- Homo sapiens (Human) 425

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Nakano,2009 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Nakano,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Nakano,2009 support certain FeatureDetection

o  Switches



This ELM instance is part of the following 3 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P84022 is implicated in the following 16 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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