| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI001963 | P25322 Ccnd1 CCND1_MOUSE |
283 | 288 | EVEEEAGLACTPTDVRDVDI | TP | --- | Mus musculus (House mouse) | 295 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Liou,2002 | support | certain | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Liou,2002 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q9QUR7) PIN1_MOUSE | PF00397
(WW)
WW domain |
7 | 37 | [mitab][xml] |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000048:
Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.
Pathways
- AGE RAGE signaling pathway in diabetic complications
- AMPK signaling pathway
- Acute myeloid leukemia
- Apelin signaling pathway
- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis receptor activation
- Chronic myeloid leukemia
- Colorectal cancer
- Cushing syndrome
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- Focal adhesion
- FoxO signaling pathway
- Gastric cancer
- Glioma
- Hedgehog signaling pathway
- Hepatitis C
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- JAK STAT signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Measles
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- Oxytocin signaling pathway
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Prolactin signaling pathway
- Prostate cancer
- Proteoglycans in cancer
- Small cell lung cancer
- Thyroid cancer
- Thyroid hormone signaling pathway
- Tight junction
- Viral carcinogenesis
- Viral myocarditis
- Wnt signaling pathway
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement