The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001960 O15350 TP73
P73_HUMAN
479 484 AQSMVSGSHCTPPPPYHADP TP --- Homo sapiens (Human) 636

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Mantovani,2004 support certain
experimental MI:0434 phosphatase assay in vitro Mantovani,2004 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Mantovani,2004 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Mantovani,2004 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q13526) PIN1_HUMAN PF00397 (WW)
WW domain
7 37 [mitab][xml]

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence O15350 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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