The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003684 Q96T88 UHRF1
UHRF1_HUMAN
646 650 SPRTGKGKWKRKSAGGGPSR TP --- Homo sapiens (Human) 793

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Pfoh,2015 support likely
experimental MI:0053 fluorescence polarization spectroscopy in vitro Pfoh,2015 support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Pfoh,2015 support likely
experimental MI:0096 pull down in vivo/in vitro Pfoh,2015 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q93009) UBP7_HUMAN PF12436 (USP7_ICP0_bdg)
ICP0-binding domain of Ubiquitin-specific protease 7
620 865 5.2/6.0 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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