| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003681 | Q00987 MDM2 MDM2_HUMAN |
334 | 338 | ENWLPEDKGKDKGEISEKAK | U | --- | Homo sapiens (Human) | 491 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0728 | gal4 vp16 complementation | in vitro | Ma,2010 | support | not specified | InteractionDetection |
| experimental | MI:0997 | ubiquitinase assay | in vitro | Ma,2010 | support | not specified | InteractionDetection |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Ma,2010 | support | not specified | |
| experimental | MI:0096 | pull down | in vivo/in vitro | Ma,2010 | support | not specified | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q93009) UBP7_HUMAN | PF12436
(USP7_ICP0_bdg)
ICP0-binding domain of Ubiquitin-specific protease 7 |
620 | 865 | [mitab][xml] |
Pathways
- Bladder cancer
- C type lectin receptor signaling pathway
- Cell cycle
- Cellular senescence
- Chronic myeloid leukemia
- Endocrine resistance
- Endocytosis
- Epstein Barr virus infection
- FoxO signaling pathway
- Glioma
- Human cytomegalovirus infection
- Human papillomavirus infection
- Melanoma
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Shigellosis
- Thyroid hormone signaling pathway
- Transcriptional misregulation in cancer
- Ubiquitin mediated proteolysis
- Viral carcinogenesis
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement