The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002689 Q12968 NFATC3
NFAC3_HUMAN
393 396 KDSCGDQFLSVPSPFTWSKP TP --- Homo sapiens (Human) 1075

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Park,2000 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Liu,2001 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Liu,2001 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Liu,2001 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Martinez-Martinez,2006 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Park,2000 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P63098) CANB1_HUMAN PF13499 (EF_hand_7)
EF-hand domain pair
[mitab][xml]
(Q08209) PP2BA_HUMAN PF00149 (Metallophos)
Calcineurin-like phosphoesterase
83 285 [mitab][xml]

o  Pathways

KEGG: The sequence Q12968 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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