The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003170 O96017 CHEK2
CHK2_HUMAN
71 76 ETVSTQELYSIPEDQEPEDQ TP --- Homo sapiens (Human) 543

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Hertz,2016 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Hertz,2016 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Hertz,2016 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q15172) 2A5A_HUMAN IPR016024 (Armadillo-type fold)
This entry represents a structural domain with an armadillo (ARM)-like fold, consisting of a multi-helical fold comprised of two curved layers of alpha helices arranged in a regular right-handed s...
0.75/0.75 [mitab][xml]

o  Pathways

KEGG: The sequence O96017 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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