The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003165 O60566 BUB1B
BUB1B_HUMAN
669 674 QTLSIKKLSPIIEDSREATH TP 5JJA  
5K6S  
5SWF  
Homo sapiens (Human) 1050

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Wang,2016 support certain InteractionDetection FeatureDetection
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Wang,2016 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Hertz,2016 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Hertz,2016 support certain FeatureDetection
experimental MI:0081 peptide array Hertz,2016 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Wang,2016 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Wang,2016 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Wang,2016 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q15172) 2A5A_HUMAN IPR016024 (Armadillo-type fold)
This entry represents a structural domain with an armadillo (ARM)-like fold, consisting of a multi-helical fold comprised of two curved layers of alpha helices arranged in a regular right-handed s...
4.6/4.6 [mitab][xml]
(Q13362) 2A5G_HUMAN IPR016024 (Armadillo-type fold)
This entry represents a structural domain with an armadillo (ARM)-like fold, consisting of a multi-helical fold comprised of two curved layers of alpha helices arranged in a regular right-handed s...
2.41/3.41 [mitab][xml]

o  Pathways

KEGG: The sequence O60566 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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