| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003179 | O43524 FOXO3 FOXO3_HUMAN |
448 | 453 | NSLRQSPMQTIQENKPATFS | TP | --- | Homo sapiens (Human) | 673 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Hertz,2016 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Hertz,2016 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q15172) 2A5A_HUMAN | IPR016024
(Armadillo-type fold)
This entry represents a structural domain with an armadillo (ARM)-like fold, consisting of a multi-helical fold comprised of two curved layers of alpha helices arranged in a regular right-handed s... |
17.0/17.0 | [mitab][xml] |
Pathways
- AMPK signaling pathway
- Cellular senescence
- Chemical carcinogenesis reactive oxygen species
- Chemokine signaling pathway
- EGFR tyrosine kinase inhibitor resistance
- Endometrial cancer
- FoxO signaling pathway
- Longevity regulating pathway
- Longevity regulating pathway multiple species
- Mitophagy animal
- Neurotrophin signaling pathway
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Prolactin signaling pathway
- Shigellosis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement