The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004432 Q9HD42 CHMP1A
CHM1A_HUMAN
185 195 ESSVRSQEDQLSRRLAALRN TP 2JQ9  
2YMB  
4A5X  
Homo sapiens (Human) 196

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0018 two hybrid in vivo Hadders,2012 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Hadders,2012 support certain InteractionDetection FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Hadders,2012 support certain InteractionDetection
experimental MI:0119 mutation decreasing interaction in vivo/in vitro Stuchell-Brereton,2007 support certain InteractionDetection
experimental MI:0968 biosensor Stuchell-Brereton,2007 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Stuchell-Brereton,2007 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Stuchell-Brereton,2007 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q8WV92) MITD1_HUMAN PF04212 (MIT)
MIT (microtubule interacting and transport) domain
13 77 [mitab][xml]
(Q9UN37) VPS4A_HUMAN PF04212 (MIT)
MIT (microtubule interacting and transport) domain
6 72 33.0/35.0 [mitab][xml]

o  Pathways

KEGG: The sequence Q9HD42 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org