ELM - instance DOC_MAPK_RevD_3 in sequence Q9BUB5 at position 434

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002943	Q9BUB5 MKNK1 MKNK1_HUMAN	434	448	CSMKLSPPCKSRLARRRALA	TP	2Y9Q	Homo sapiens (Human)	465

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	likely	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Garai,2012	support	likely
experimental	MI:0573	mutation disrupting interaction	in vivo/in vitro	Tanoue,2000	support	likely
experimental	MI:0051	fluorescence technology		Garai,2012	support	likely	InteractionDetection
experimental	MI:0405	competition binding	in vitro	Garai,2012	support	likely	InteractionDetection
experimental	MI:0114	x-ray crystallography	in vitro	Garai,2012	support	likely	InteractionDetection FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P28482) MK01_HUMAN	PF00069 (Pkinase) Protein kinase domain	25	313	0.7/0.7	[mitab][xml]
(Q16539) MK14_HUMAN	PF00069 (Pkinase) Protein kinase domain	24	308	0.6/0.6	[mitab][xml]

Pathways

KEGG: The sequence Q9BUB5 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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