The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002943 Q9BUB5 MKNK1
MKNK1_HUMAN
434 448 CSMKLSPPCKSRLARRRALA TP 2Y9Q  
Homo sapiens (Human) 465

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Garai,2012 support likely
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Tanoue,2000 support likely
experimental MI:0051 fluorescence technology Garai,2012 support likely InteractionDetection
experimental MI:0405 competition binding in vitro Garai,2012 support likely InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Garai,2012 support likely InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P28482) MK01_HUMAN PF00069 (Pkinase)
Protein kinase domain
25 313 0.7/0.7 [mitab][xml]
(Q16539) MK14_HUMAN PF00069 (Pkinase)
Protein kinase domain
24 308 0.6/0.6 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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