The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002942 Q15418 RPS6KA1
Homo sapiens (Human) 735

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Garai,2012 support certain
experimental MI:0424 protein kinase assay in vitro Alexa,2015 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Alexa,2015 support certain
experimental MI:0051 fluorescence technology Garai,2012 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Garai,2012 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Garai,2012 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P28482) MK01_HUMAN PF00069 (Pkinase)
Protein kinase domain
25 313 0.5/0.5 [mitab][xml]
(Q16539) MK14_HUMAN PF00069 (Pkinase)
Protein kinase domain
24 308 11.5/11.5 [mitab][xml]

o  Pathways

KEGG: The sequence Q15418 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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