ELM - instance DOC_MAPK_RevD_3 in sequence O75582 at position 730

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002944	O75582 RPS6KA5 KS6A5_HUMAN	730	744	EGFCLQNVDKAPLAKRRKMK	TP	---	Homo sapiens (Human)	802

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	likely	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Garai,2012	support	likely
experimental	MI:0573	mutation disrupting interaction	in vivo/in vitro	McCoy,2005	support	likely
experimental	MI:0007	anti tag coimmunoprecipitation	in vivo	McCoy,2005	support	likely	InteractionDetection
experimental	MI:0051	fluorescence technology		Garai,2012	support	likely	InteractionDetection
experimental	MI:0405	competition binding	in vitro	Garai,2012	support	likely	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P28482) MK01_HUMAN	PF00069 (Pkinase) Protein kinase domain	25	313	1.2/1.2	[mitab][xml]
(Q16539) MK14_HUMAN	PF00069 (Pkinase) Protein kinase domain	24	308	0.4/0.4	[mitab][xml]

Pathways

KEGG: The sequence O75582 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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