The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002944 O75582 RPS6KA5
KS6A5_HUMAN
730 744 EGFCLQNVDKAPLAKRRKMK TP --- Homo sapiens (Human) 802

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Garai,2012 support likely
experimental MI:0573 mutation disrupting interaction in vivo/in vitro McCoy,2005 support likely
experimental MI:0007 anti tag coimmunoprecipitation in vivo McCoy,2005 support likely InteractionDetection
experimental MI:0051 fluorescence technology Garai,2012 support likely InteractionDetection
experimental MI:0405 competition binding in vitro Garai,2012 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P28482) MK01_HUMAN PF00069 (Pkinase)
Protein kinase domain
25 313 1.2/1.2 [mitab][xml]
(Q16539) MK14_HUMAN PF00069 (Pkinase)
Protein kinase domain
24 308 0.4/0.4 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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