| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI003289 |  P52564 MAP2K6 MP2K6_HUMAN  | 
        7 | 15 | SQSKGKKRNPGLKIPKEAFE | TP | --- | Homo sapiens (Human) | 334 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0809 | bimolecular fluorescence complementation | Zeke,2015 | support | certain | InteractionDetection | |
| experimental | MI:0049 | filter binding | Zeke,2015 | support | certain | InteractionDetection | 
  Interactions 
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes | 
|---|---|---|---|---|---|
| (Q16539) MK14_HUMAN |  PF00069
                  (Pkinase) 
                  Protein kinase domain  | 
             24 | 308 | [mitab][xml] | 
  Pathways 
- Amyotrophic lateral sclerosis
 - Cellular senescence
 - Epstein Barr virus infection
 - Fc epsilon RI signaling pathway
 - Fluid shear stress and atherosclerosis
 - GnRH signaling pathway
 - Growth hormone synthesis, secretion and action
 - Hepatitis B
 - Human cytomegalovirus infection
 - Human immunodeficiency virus 1 infection
 - Inflammatory mediator regulation of TRP channels
 - Kaposi sarcoma associated herpesvirus infection
 - Lipid and atherosclerosis
 - MAPK signaling pathway
 - Osteoclast differentiation
 - PD L1 expression and PD 1 checkpoint pathway in cancer
 - Pathways of neurodegeneration multiple diseases
 - Rap1 signaling pathway
 - Salmonella infection
 - TNF signaling pathway
 - Toll like receptor signaling pathway
 - Toxoplasmosis
 - Yersinia infection
 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
