The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003065 P35568 IRS1
IRS1_HUMAN
857 863 TNSRLARPTRLSLGDPKAST TP --- Homo sapiens (Human) 1242

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0053 fluorescence polarization spectroscopy in vitro Zeke,2015 support certain InteractionDetection
experimental MI:0089 protein array Zeke,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P45983) MK08_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]

o  Pathways

KEGG: The sequence P35568 is implicated in the following 13 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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