The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003316 P54829 PTPN5
PTN5_HUMAN
239 251 SMGLQERRGSNVSLTLDMCT TP --- Homo sapiens (Human) 565

o  Instance evidence

Evidence classPSMIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0826 x ray scattering Francis,2013 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Francis,2013 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Francis,2013 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Francis,2013 support certain InteractionDetection FeatureDetection
experimental MI:0424 protein kinase assay in vitro Pulido,1999 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P63085) MK01_MOUSE PF00069 (Pkinase)
Protein kinase domain
23 311 [mitab][xml]
(Q63844) MK03_MOUSE PF00069 (Pkinase)
Protein kinase domain
43 331 [mitab][xml]
(Q16539) MK14_HUMAN PF00069 (Pkinase)
Protein kinase domain
24 308 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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