The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000069 P46527 CDKN1B
CDN1B_HUMAN
27 37 HPKPSACRNLFGPVDHEELT TP 1H27  
pdb:1H27 1JSU  
pdb:1JSU
Homo sapiens (Human) 198

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Luo,1995 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Luo,1995 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lowe,2002 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Russo,1996 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kwon,1998 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P24864) CCNE1_HUMAN PF00134 (Cyclin_N)
Cyclin, N-terminal domain
115 242 [mitab][xml]

o  Pathways

KEGG: The sequence P46527 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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