| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI000069 | P46527 CDKN1B CDN1B_HUMAN |
27 | 37 | HPKPSACRNLFGPVDHEELT | TP |
1H27 
1JSU 
6P8E |
Homo sapiens (Human) | 198 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0114 | x-ray crystallography | in vitro | Guiley,2019 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Luo,1995 | support | certain | FeatureDetection |
| experimental | MI:0096 | pull down | in vivo/in vitro | Luo,1995 | support | certain | InteractionDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Lowe,2002 | support | certain | InteractionDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Russo,1996 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Kwon,1998 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P24864) CCNE1_HUMAN | PF00134
(Cyclin_N)
Cyclin, N-terminal domain |
115 | 242 | [mitab][xml] |
Pathways
- AGE RAGE signaling pathway in diabetic complications
- Cell cycle
- Chronic myeloid leukemia
- Cushing syndrome
- Endocrine resistance
- Epstein Barr virus infection
- ErbB signaling pathway
- FoxO signaling pathway
- Gastric cancer
- HIF 1 signaling pathway
- Human papillomavirus infection
- Measles
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
- Transcriptional misregulation in cancer
- Viral carcinogenesis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement