The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003324 O97143 SAK
PLK4_DROME
292 297 SQSMESGDSGIITFASSDSR TP --- Drosophila melanogaster (Fruit fly) 769

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Cunha-Ferreira,2009 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Klebba,2013 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Klebba,2013 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Cunha-Ferreira,2009 support certain FeatureDetection
experimental MI:0069 mass spectrometry studies of complexes Cunha-Ferreira,2009 support certain InteractionDetection
experimental MI:0113 western blot in vitro Cunha-Ferreira,2009 support certain ParticipantIdentification FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Cunha-Ferreira,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Rogers,2009 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Rogers,2009 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O44382) O44382_DROME PF00400 (WD40)
WD domain, G-beta repeat
[mitab][xml]

o  Pathways

KEGG: The sequence O97143 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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