Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004149 | P24385 CCND1 CCND1_HUMAN |
289 | 295 | EEEEEVDLACTPTDVRDVDI | TP |
5VZU |
Homo sapiens (Human) | 295 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:1297 | phosphoamino acid analysis | Li,2018 | support | certain | FeatureDetection | |
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Li,2018 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Li,2018 | support | certain | FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Li,2018 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q5XUX0) FBX31_HUMAN | PF12014
(Cyclin_D1_bind)
Cyclin D1 binding domain |
286 | 515 | 2.3/3.1 | [mitab][xml] |
Pathways
KEGG: The sequence P24385 is implicated in the following 47 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- AMPK signaling pathway
- Acute myeloid leukemia
- Apelin signaling pathway
- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis receptor activation
- Chronic myeloid leukemia
- Colorectal cancer
- Cushing syndrome
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- Focal adhesion
- FoxO signaling pathway
- Gastric cancer
- Glioma
- Hedgehog signaling pathway
- Hepatitis C
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- JAK STAT signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Measles
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- Oxytocin signaling pathway
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Prolactin signaling pathway
- Prostate cancer
- Proteoglycans in cancer
- Small cell lung cancer
- Thyroid cancer
- Thyroid hormone signaling pathway
- Tight junction
- Viral carcinogenesis
- Viral myocarditis
- Wnt signaling pathway
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement