The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001401 P46531 NOTCH1
NOTC1_HUMAN
2508 2515 LQVPEHPFLTPSPESPDQWS TP --- Homo sapiens (Human) 2555

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Oberg,2001 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Wu,2001 support certain InteractionDetection
experimental MI:0517 radiolabel in vitro Wu,2001 support likely
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Oberg,2001 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Oberg,2001 support certain InteractionDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P46531 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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