The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002518 A7XXZ0 LOC100134911
A7XXZ0_SOLLC
199 216 PIARRNSLTRFLEKRKDRVT TP --- Solanum lycopersicum (Tomato) 252

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0521 his tag in vivo/in vitro/in silico Katsir,2008 support likely
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0521 his tag in vivo/in vitro/in silico Thines,2007 support likely
experimental MI:0018 two hybrid in vivo Thines,2007 support likely InteractionDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
  • SWTI000722:
    ELM Switch SWTI000722

    Binding of LOC100134911 to Coi1, an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in the JAZ protein. Subsequent ubiquitylation of the JAZ protein by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate.

o  Pathways

KEGG: The sequence A7XXZ0 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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