The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002559 O08899 Rgs4
RGS4_MOUSE
1 3 MCKGLAGLPASCLRSAKDMK TP --- Mus musculus (House mouse) 205

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Hu,2005 support certain InteractionDetection
experimental MI:0517 radiolabel in vitro Hu,2005 support certain
experimental MI:0113 western blot in vitro Hu,2005 support certain ParticipantIdentification FeatureDetection
experimental MI:0032 de novo protein sequencing by mass spectrometry in vivo/in vitro Hu,2005 support certain ParticipantIdentification FeatureDetection
experimental MI:0039 edman degradation in vitro Hu,2005 support certain ParticipantIdentification
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Hu,2005 support certain
experimental MI:0788 knock out in vivo Hu,2005 support certain
experimental MI:0039 edman degradation in vitro Davydov,2000 support certain ParticipantIdentification
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Davydov,2000 support certain
experimental MI:0788 knock out in vivo Davydov,2000 support certain
experimental MI:0517 radiolabel in vitro Davydov,2000 support certain
experimental MI:0113 western blot in vitro Davydov,2000 support certain ParticipantIdentification FeatureDetection
experimental MI:0405 competition binding in vitro Davydov,2000 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Lee,2005 support certain
experimental MI:0788 knock out in vivo Lee,2005 support certain
experimental MI:0517 radiolabel in vitro Lee,2005 support certain
experimental MI:0113 western blot in vitro Lee,2005 support certain ParticipantIdentification FeatureDetection
experimental MI:0997 ubiquitinase assay in vitro Lee,2005 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Lee,2005 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O70481) UBR1_MOUSE PF02207 (zf-UBR)
Putative zinc finger in N-recognin (UBR box)
97 167 [mitab][xml]
(Q6WKZ8) UBR2_MOUSE PF02207 (zf-UBR)
Putative zinc finger in N-recognin (UBR box)
97 167 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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