ELM - instance DEG_Kelch_Keap1_2 in sequence Q60795 at position 26

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002832	Q60795 Nfe2l2 NF2L2_MOUSE	26	32	IDILWRQDIDLGVSREVFDF	TP	2DYH 3WN7	Mus musculus (House mouse)	597

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Fukutomi,2014	support	certain
experimental	MI:0065	isothermal titration calorimetry	in vitro	Fukutomi,2014	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Fukutomi,2014	support	certain	FeatureDetection
experimental	MI:0107	surface plasmon resonance	in vitro	Fukutomi,2014	support	certain	InteractionDetection FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Fukutomi,2014	support	certain	InteractionDetection FeatureDetection
experimental	MI:0997	ubiquitinase assay	in vitro	Tong,2007	support	certain	InteractionDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Tong,2007	support	certain	InteractionDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Tong,2007	support	certain	FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Tong,2007	support	certain	InteractionDetection FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(Q9Z2X8) KEAP1_MOUSE	PF01344 (Kelch_1) Kelch motif				[mitab][xml]

Pathways

KEGG: The sequence Q60795 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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