The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004598 O94979 SEC31A
SC31A_HUMAN
957 962 GASFQHGGPGAPPSSSAYAL TP --- Homo sapiens (Human) 1220

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0033 deletion analysis Jin,2012 support certain FeatureDetection
experimental MI:0427 Identification by mass spectrometry Jin,2012 support certain ParticipantIdentification
experimental MI:0004 affinity chromatography technology in vivo/in vitro Jin,2012 support certain InteractionDetection
experimental MI:0997 ubiquitinase assay in vitro Jin,2012 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Jin,2012 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Jin,2012 support certain InteractionDetection
predicted MI:0363 inferred by author in silico Chen,2020 support not specified InteractionDetection ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q53G59) KLH12_HUMAN IPR006652 (Kelch repeat type 1)
Kelch is a 50-residue motif, named after the Drosophila mutant in which it was first identified
281 567 [mitab][xml]

o  Pathways

KEGG: The sequence O94979 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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