The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004556 O14641 DVL2
DVL2_HUMAN
698 703 PVPPAVQPPGAPPVRDLGSV TP --- Homo sapiens (Human) 736

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0006 anti bait coimmunoprecipitation Wei,2012 support certain InteractionDetection
experimental MI:0006 anti bait coimmunoprecipitation Zhu,2022 support certain InteractionDetection
experimental MI:2163 by homology in silico Chen,2020 support certain ParticipantIdentification
experimental MI:0363 inferred by author in silico Chen,2020 support certain InteractionDetection ParticipantIdentification FeatureDetection
experimental MI:0081 peptide array Chen,2020 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q53G59) KLH12_HUMAN IPR006652 (Kelch repeat type 1)
Kelch is a 50-residue motif, named after the Drosophila mutant in which it was first identified
281 567 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org