The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001945 Q9NQR1 SETD8
SETD8_HUMAN
220 231 TQQNRKLTDFYPVRRSSRKS TP --- Homo sapiens (Human) 393

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0256 rna interference in vivo Centore,2010 support certain InteractionDetection
experimental MI:0113 western blot in vitro Centore,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Centore,2010 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Centore,2010 support certain FeatureDetection
experimental MI:0051 fluorescence technology Jorgensen,2011 support certain InteractionDetection
experimental MI:0256 rna interference in vivo Jorgensen,2011 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Jorgensen,2011 support certain
experimental MI:0997 ubiquitinase assay in vitro Jorgensen,2011 support certain InteractionDetection
experimental MI:0113 western blot in vitro Jorgensen,2011 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9NZJ0) DTL_HUMAN PF00400 (WD40)
WD domain, G-beta repeat
[mitab][xml]
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 [mitab][xml]

o  Pathways

KEGG: The sequence Q9NQR1 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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