The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
DEG_APCC_TPR_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002491 P53197 CDH1
CDH1_YEAST 		564 566 KPKAKVQPNSLIFDAFNQIR TP --- Saccharomyces cerevisiae S288c 566

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0676 tandem affinity purification Kraft,2005 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Kraft,2005 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Kraft,2005 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Kraft,2005 support certain InteractionDetection
experimental MI:0997 ubiquitinase assay in vitro Matyskiela,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Matyskiela,2009 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Matyskiela,2009 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Matyskiela,2009 support certain InteractionDetection
experimental MI:0517 radiolabel in vitro Passmore,2003 support certain
experimental MI:0404 comigration in non denaturing gel electrophoresis in vivo Passmore,2003 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Passmore,2003 support certain
experimental MI:0997 ubiquitinase assay in vitro Passmore,2003 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Passmore,2003 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P38042) CDC27_YEAST SM00028 (TPR)
Tetratricopeptide repeats. 		[mitab][xml]
(P38042) CDC27_YEAST SM00028 (TPR)
Tetratricopeptide repeats. 		[mitab][xml]

o  Pathways

KEGG: The sequence P53197 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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