The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001908 P36956 SREBF1
SRBP1_HUMAN
457 461 SGGSGSDSEPDSPVFEDSKA TP --- Homo sapiens (Human) 1147

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Wang,1995 support likely InteractionDetection
experimental MI:0113 western blot in vitro Wang,1995 support likely ParticipantIdentification FeatureDetection
experimental MI:0039 edman degradation in vitro Wang,1995 support likely ParticipantIdentification
experimental MI:0074 mutation analysis in vivo/in vitro Wang,1995 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42574) CASP3_HUMAN PF00656 (Peptidase_C14)
Caspase domain
45 275 [mitab][xml]

o  Pathways

KEGG: The sequence P36956 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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