The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

Pathways linked from ELM instances

The following list contains those pathways annotated at the "Kyoto Encyclopedia of Genes and Genomes" (KEGG) database for which at least one sequence is stored in the ELM database (containing at least one ELM instance). Sequences have been mapped from Uniprot to KEGG and colored in the pathway according to a simple colorscheme.

TaxonPathway entryPathway name# Instances# Sequences
hsa02010 ABC transporters 5 3
hsa05221 Acute myeloid leukemia 45 21
rno05221 Acute myeloid leukemia 3 3
mmu05221 Acute myeloid leukemia 2 2
hsa04520 Adherens junction 42 19
gga04520 Adherens junction 2 2
mmu04520 Adherens junction 3 3
xla04520 Adherens junction 1 1
rno04520 Adherens junction 2 2
hsa04920 Adipocytokine signaling pathway 22 13
mmu04920 Adipocytokine signaling pathway 4 4
rno04920 Adipocytokine signaling pathway 4 1
hsa04261 Adrenergic signaling in cardiomyocytes 17 14
mmu04261 Adrenergic signaling in cardiomyocytes 3 2
bta04261 Adrenergic signaling in cardiomyocytes 1 1
rno04261 Adrenergic signaling in cardiomyocytes 4 4
ocu04261 Adrenergic signaling in cardiomyocytes 1 1
rno05143 African trypanosomiasis 1 1
hsa05143 African trypanosomiasis 2 2
hsa05034 Alcoholism 31 20
mmu05034 Alcoholism 4 4
hsa04960 Aldosterone regulated sodium reabsorption 13 8
rno04960 Aldosterone regulated sodium reabsorption 6 3
hsa05330 Allograft rejection 5 4
mmu05330 Allograft rejection 1 1
hsa05010 Alzheimer's disease 23 14
rno05010 Alzheimer's disease 3 3
mmu05010 Alzheimer's disease 2 2
ocu05010 Alzheimer's disease 1 1
hsa00520 Amino sugar and nucleotide sugar metabolism 1 1
hsa05146 Amoebiasis 24 13
bta05146 Amoebiasis 1 1
mmu05146 Amoebiasis 2 2
hsa05031 Amphetamine addiction 21 10
bta05031 Amphetamine addiction 1 1
mmu05031 Amphetamine addiction 3 3
ocu05031 Amphetamine addiction 1 1
rno05031 Amphetamine addiction 3 3
hsa04152 AMPK signaling pathway 31 18
mmu04152 AMPK signaling pathway 6 6
bta04152 AMPK signaling pathway 1 1
rno04152 AMPK signaling pathway 7 4
rno05014 Amyotrophic lateral sclerosis (ALS) 3 3
hsa05014 Amyotrophic lateral sclerosis (ALS) 25 8
hsa04612 Antigen processing and presentation 13 10
mmu04612 Antigen processing and presentation 2 2
rno04612 Antigen processing and presentation 1 1
ssc04612 Antigen processing and presentation 1 1
hsa04210 Apoptosis 41 18
rno04210 Apoptosis 1 1
bta04210 Apoptosis 3 2
mmu04210 Apoptosis 1 1
hsa00590 Arachidonic acid metabolism 1 1
mmu05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 3 2
hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 18 9
ocu05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 1 1
rno05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 1 1
hsa00053 Ascorbate and aldarate metabolism 1 1
rno05310 Asthma 1 1
hsa05310 Asthma 3 2
mmu05310 Asthma 1 1
hsa05320 Autoimmune thyroid disease 6 5
mmu05320 Autoimmune thyroid disease 1 1
mmu04360 Axon guidance 5 5
hsa04360 Axon guidance 29 19
rno04360 Axon guidance 2 2
hsa05100 Bacterial invasion of epithelial cells 37 18
mmu05100 Bacterial invasion of epithelial cells 3 3
rno05100 Bacterial invasion of epithelial cells 4 4
hsa05217 Basal cell carcinoma 29 7
rno05217 Basal cell carcinoma 1 1
mmu05217 Basal cell carcinoma 4 4
hsa03022 Basal transcription factors 1 1
hsa03410 Base excision repair 15 9
sce03410 Base excision repair 5 5
spo03410 Base excision repair 1 1
hsa04662 B cell receptor signaling pathway 52 28
ssc04662 B cell receptor signaling pathway 1 1
mmu04662 B cell receptor signaling pathway 8 8
rno04662 B cell receptor signaling pathway 1 1
bta04976 Bile secretion 1 1
hsa04976 Bile secretion 7 4
mmu04976 Bile secretion 1 1
rno04976 Bile secretion 2 2
sce01230 Biosynthesis of amino acids 1 1
sce01130 Biosynthesis of antibiotics 1 1
hsa01130 Biosynthesis of antibiotics 2 2
sce01110 Biosynthesis of secondary metabolites 1 1
hsa05219 Bladder cancer 55 17
mmu05219 Bladder cancer 1 1
rno05219 Bladder cancer 1 1
bta04020 Calcium signaling pathway 1 1
hsa04020 Calcium signaling pathway 34 22
mmu04020 Calcium signaling pathway 1 1
ocu04020 Calcium signaling pathway 1 1
rno04020 Calcium signaling pathway 5 4
hsa04024 cAMP signaling pathway 60 34
rno04024 cAMP signaling pathway 7 7
ssc04024 cAMP signaling pathway 1 1
bta04024 cAMP signaling pathway 1 1
mmu04024 cAMP signaling pathway 4 4
ocu04024 cAMP signaling pathway 1 1
rno04973 Carbohydrate digestion and absorption 2 2
hsa04973 Carbohydrate digestion and absorption 4 2
sce01200 Carbon metabolism 1 1
hsa01200 Carbon metabolism 1 1
mmu04260 Cardiac muscle contraction 2 1
rno04260 Cardiac muscle contraction 2 2
ocu04260 Cardiac muscle contraction 1 1
hsa04260 Cardiac muscle contraction 3 3
hsa04514 Cell adhesion molecules (CAMs) 16 14
mmu04514 Cell adhesion molecules (CAMs) 3 3
ecb04514 Cell adhesion molecules (CAMs) 1 1
rno04514 Cell adhesion molecules (CAMs) 1 1
hsa04110 Cell cycle 100 37
mmu04110 Cell cycle 6 5
xla04110 Cell cycle 4 4
spo04111 Cell cycle yeast 6 6
sce04111 Cell cycle yeast 24 16
hsa05230 Central carbon metabolism in cancer 47 15
mmu05230 Central carbon metabolism in cancer 1 1
hsa04022 cGMP PKG signaling pathway 51 32
rno04022 cGMP PKG signaling pathway 8 5
ssc04022 cGMP PKG signaling pathway 1 1
ocu04022 cGMP PKG signaling pathway 1 1
mmu04022 cGMP PKG signaling pathway 1 1
hsa05142 Chagas disease (American trypanosomiasis) 44 22
mmu05142 Chagas disease (American trypanosomiasis) 6 5
rno05142 Chagas disease (American trypanosomiasis) 1 1
hsa05204 Chemical carcinogenesis 2 2
hsa04062 Chemokine signaling pathway 63 35
bta04062 Chemokine signaling pathway 2 2
mmu04062 Chemokine signaling pathway 7 7
rno04062 Chemokine signaling pathway 6 6
hsa05231 Choline metabolism in cancer 46 20
mmu05231 Choline metabolism in cancer 4 4
rno05231 Choline metabolism in cancer 2 2
hsa04725 Cholinergic synapse 22 17
bta04725 Cholinergic synapse 1 1
mmu04725 Cholinergic synapse 3 3
ocu04725 Cholinergic synapse 1 1
rno04725 Cholinergic synapse 2 2
hsa05220 Chronic myeloid leukemia 74 28
rno05220 Chronic myeloid leukemia 1 1
mmu05220 Chronic myeloid leukemia 3 3
mmu04713 Circadian entrainment 4 4
bta04713 Circadian entrainment 1 1
hsa04713 Circadian entrainment 12 9
ocu04713 Circadian entrainment 1 1
rno04713 Circadian entrainment 4 4
mmu04710 Circadian rhythm 2 2
ath04712 Circadian rhythm plant 1 1
hsa05030 Cocaine addiction 24 10
bta05030 Cocaine addiction 1 1
mmu05030 Cocaine addiction 2 2
rno05030 Cocaine addiction 1 1
hsa04966 Collecting duct acid secretion 1 1
hsa05210 Colorectal cancer 62 18
rno05210 Colorectal cancer 2 2
mmu05210 Colorectal cancer 5 5
hsa04610 Complement and coagulation cascades 16 12
bta04610 Complement and coagulation cascades 2 2
hsa00270 Cysteine and methionine metabolism 2 1
mmu04060 Cytokine cytokine receptor interaction 3 3
hsa04060 Cytokine cytokine receptor interaction 44 28
hsa04623 Cytosolic DNA sensing pathway 13 7
mmu04623 Cytosolic DNA sensing pathway 1 1
mmu05414 Dilated cardiomyopathy 3 2
bta05414 Dilated cardiomyopathy 1 1
hsa05414 Dilated cardiomyopathy 16 10
ocu05414 Dilated cardiomyopathy 1 1
rno05414 Dilated cardiomyopathy 2 2
sce03030 DNA replication 5 5
hsa03030 DNA replication 6 6
spo03030 DNA replication 1 1
hsa04728 Dopaminergic synapse 13 10
bta04728 Dopaminergic synapse 1 1
mmu04728 Dopaminergic synapse 4 4
rno04728 Dopaminergic synapse 4 4
ocu04728 Dopaminergic synapse 1 1
hsa04320 Dorso ventral axis formation 11 5
xla04320 Dorso ventral axis formation 1 1
mmu04320 Dorso ventral axis formation 1 1
hsa00982 Drug metabolism cytochrome P450 1 1
hsa00983 Drug metabolism other enzymes 1 1
hsa04512 ECM receptor interaction 21 13
rno04512 ECM receptor interaction 1 1
mmu04512 ECM receptor interaction 2 2
bta04512 ECM receptor interaction 1 1
hsa04961 Endocrine and other factor regulated calcium reabsorption 8 7
bta04961 Endocrine and other factor regulated calcium reabsorption 1 1
mmu04961 Endocrine and other factor regulated calcium reabsorption 1 1
rno04961 Endocrine and other factor regulated calcium reabsorption 2 2
hsa04144 Endocytosis 77 45
rno04144 Endocytosis 11 7
gga04144 Endocytosis 2 2
bta04144 Endocytosis 4 3
mmu04144 Endocytosis 10 10
cel04144 Endocytosis 1 1
ssc04144 Endocytosis 1 1
sce04144 Endocytosis 3 3
dme04144 Endocytosis 1 1
hsa05213 Endometrial cancer 63 20
rno05213 Endometrial cancer 2 2
mmu05213 Endometrial cancer 4 4
hsa05120 Epithelial cell signaling in Helicobacter pylori infection 38 15
hsa05169 Epstein Barr virus infection 95 34
bta05169 Epstein Barr virus infection 1 1
mmu05169 Epstein Barr virus infection 7 7
rno05169 Epstein Barr virus infection 2 2
ssc05169 Epstein Barr virus infection 1 1
cel04012 ErbB signaling pathway 1 1
rno04012 ErbB signaling pathway 5 5
mmu04012 ErbB signaling pathway 5 5
gga04012 ErbB signaling pathway 4 2
hsa04012 ErbB signaling pathway 70 25
xla04012 ErbB signaling pathway 1 1
hsa04915 Estrogen signaling pathway 47 26
bta04915 Estrogen signaling pathway 1 1
mmu04915 Estrogen signaling pathway 6 6
rno04915 Estrogen signaling pathway 4 4
ssc04915 Estrogen signaling pathway 2 2
hsa03460 Fanconi anemia pathway 14 7
hsa00061 Fatty acid biosynthesis 1 1
hsa01212 Fatty acid metabolism 1 1
mmu04664 Fc epsilon RI signaling pathway 6 6
hsa04664 Fc epsilon RI signaling pathway 23 15
rno04664 Fc epsilon RI signaling pathway 2 2
hsa04666 Fc gamma R mediated phagocytosis 38 24
rno04666 Fc gamma R mediated phagocytosis 6 5
mmu04666 Fc gamma R mediated phagocytosis 3 3
hsa04510 Focal adhesion 83 40
rno04510 Focal adhesion 6 6
gga04510 Focal adhesion 9 6
mmu04510 Focal adhesion 8 8
bta04510 Focal adhesion 1 1
xla04510 Focal adhesion 1 1
hsa04068 FoxO signaling pathway 62 35
xla04068 FoxO signaling pathway 2 2
mmu04068 FoxO signaling pathway 5 5
rno04068 FoxO signaling pathway 5 2
bta00051 Fructose and mannose metabolism 1 1
bta04727 GABAergic synapse 1 1
mmu04727 GABAergic synapse 1 1
hsa04727 GABAergic synapse 12 7
ocu04727 GABAergic synapse 1 1
rno04727 GABAergic synapse 4 4
bta04540 Gap junction 1 1
gga04540 Gap junction 1 1
hsa04540 Gap junction 26 13
mmu04540 Gap junction 2 2
rno04540 Gap junction 5 4
xla04540 Gap junction 1 1
bta04971 Gastric acid secretion 1 1
mmu04971 Gastric acid secretion 1 1
rno04971 Gastric acid secretion 3 3
hsa04971 Gastric acid secretion 8 5
hsa05214 Glioma 52 18
mmu05214 Glioma 2 2
hsa04922 Glucagon signaling pathway 12 9
ocu04922 Glucagon signaling pathway 1 1
bta04922 Glucagon signaling pathway 1 1
mmu04922 Glucagon signaling pathway 2 2
bta04724 Glutamatergic synapse 1 1
mmu04724 Glutamatergic synapse 2 2
hsa04724 Glutamatergic synapse 11 9
ocu04724 Glutamatergic synapse 1 1
rno04724 Glutamatergic synapse 9 8
hsa00564 Glycerophospholipid metabolism 1 1
sce00010 Glycolysis / Gluconeogenesis 1 1
hsa00531 Glycosaminoglycan degradation 1 1
mmu00604 Glycosphingolipid biosynthesis ganglio series 1 1
hsa00604 Glycosphingolipid biosynthesis ganglio series 1 1
hsa00603 Glycosphingolipid biosynthesis globo series 1 1
hsa00563 Glycosylphosphatidylinositol(GPI) anchor biosynthesis 1 1
mmu00563 Glycosylphosphatidylinositol(GPI) anchor biosynthesis 1 1
hsa00630 Glyoxylate and dicarboxylate metabolism 1 1
bta04912 GnRH signaling pathway 1 1
gga04912 GnRH signaling pathway 4 2
hsa04912 GnRH signaling pathway 41 19
mmu04912 GnRH signaling pathway 3 3
ocu04912 GnRH signaling pathway 1 1
rno04912 GnRH signaling pathway 4 4
xla04912 GnRH signaling pathway 1 1
hsa05332 Graft versus host disease 4 4
bta04340 Hedgehog signaling pathway 1 1
mmu04340 Hedgehog signaling pathway 4 4
hsa04340 Hedgehog signaling pathway 5 4
hsa04640 Hematopoietic cell lineage 25 18
mmu04640 Hematopoietic cell lineage 3 2
rno04640 Hematopoietic cell lineage 1 1
ecb04640 Hematopoietic cell lineage 1 1
hsa05161 Hepatitis B 119 46
rno05161 Hepatitis B 2 2
ssc05161 Hepatitis B 1 1
mmu05161 Hepatitis B 5 5
hsa05160 Hepatitis C 46 19
rno05160 Hepatitis C 1 1
mmu05160 Hepatitis C 2 2
hsa05168 Herpes simplex infection 56 22
mmu05168 Herpes simplex infection 4 4
gga05168 Herpes simplex infection 3 1
hsa04066 HIF 1 signaling pathway 47 21
rno04066 HIF 1 signaling pathway 2 2
hsa04390 Hippo signaling pathway 50 21
rno04390 Hippo signaling pathway 1 1
mmu04390 Hippo signaling pathway 8 7
dme04391 Hippo signaling pathway fly 1 1
hsa03440 Homologous recombination 6 5
spo03440 Homologous recombination 1 1
sce03440 Homologous recombination 1 1
xla03440 Homologous recombination 1 1
hsa05166 HTLV I infection 142 55
ssc05166 HTLV I infection 1 1
bta05166 HTLV I infection 1 1
mmu05166 HTLV I infection 14 13
rno05166 HTLV I infection 2 2
hsa05016 Huntington's disease 32 15
rno05016 Huntington's disease 2 1
mmu05016 Huntington's disease 1 1
mmu05410 Hypertrophic cardiomyopathy (HCM) 2 1
hsa05410 Hypertrophic cardiomyopathy (HCM) 13 8
ocu05410 Hypertrophic cardiomyopathy (HCM) 1 1
rno05410 Hypertrophic cardiomyopathy (HCM) 1 1
hsa05321 Inflammatory bowel disease (IBD) 28 10
ssc05321 Inflammatory bowel disease (IBD) 1 1
mmu05321 Inflammatory bowel disease (IBD) 1 1
bta04750 Inflammatory mediator regulation of TRP channels 1 1
hsa04750 Inflammatory mediator regulation of TRP channels 13 7
mmu04750 Inflammatory mediator regulation of TRP channels 1 1
rno04750 Inflammatory mediator regulation of TRP channels 2 2
hsa05164 Influenza A 47 23
mmu05164 Influenza A 4 4
rno05164 Influenza A 1 1
gga05164 Influenza A 3 1
ssc05164 Influenza A 1 1
hsa00562 Inositol phosphate metabolism 5 3
rno00562 Inositol phosphate metabolism 2 2
hsa04911 Insulin secretion 8 7
bta04911 Insulin secretion 1 1
mmu04911 Insulin secretion 1 1
rno04911 Insulin secretion 3 3
ocu04911 Insulin secretion 1 1
hsa04910 Insulin signaling pathway 40 24
rno04910 Insulin signaling pathway 7 4
ocu04910 Insulin signaling pathway 1 1
bta04910 Insulin signaling pathway 3 2
mmu04910 Insulin signaling pathway 4 4
xla04910 Insulin signaling pathway 1 1
hsa04672 Intestinal immune network for IgA production 6 5
mmu04672 Intestinal immune network for IgA production 1 1
hsa04630 Jak STAT signaling pathway 45 28
mmu04630 Jak STAT signaling pathway 3 3
hsa05134 Legionellosis 22 13
rno05134 Legionellosis 1 1
mmu05134 Legionellosis 1 1
ssc05134 Legionellosis 1 1
hsa05140 Leishmaniasis 30 14
mmu05140 Leishmaniasis 2 2
hsa04670 Leukocyte transendothelial migration 28 15
mmu04670 Leukocyte transendothelial migration 3 3
rno04670 Leukocyte transendothelial migration 2 2
hsa04730 Long term depression 13 11
rno04730 Long term depression 4 4
mmu04730 Long term depression 1 1
bta04720 Long term potentiation 1 1
hsa04720 Long term potentiation 15 12
mmu04720 Long term potentiation 2 2
ocu04720 Long term potentiation 1 1
rno04720 Long term potentiation 6 5
hsa00310 Lysine degradation 11 7
dme00310 Lysine degradation 2 2
sce00310 Lysine degradation 1 1
cel00310 Lysine degradation 1 1
cal00310 Lysine degradation 1 1
spo00310 Lysine degradation 1 1
hsa04142 Lysosome 14 14
bta04142 Lysosome 2 2
mmu04142 Lysosome 1 1
hsa05144 Malaria 11 8
mmu05144 Malaria 2 2
cel04010 MAPK signaling pathway 1 1
hsa04010 MAPK signaling pathway 108 48
ssc04010 MAPK signaling pathway 2 2
mmu04010 MAPK signaling pathway 12 11
bta04010 MAPK signaling pathway 2 2
rno04010 MAPK signaling pathway 4 4
ocu04010 MAPK signaling pathway 1 1
gga04010 MAPK signaling pathway 3 1
xla04010 MAPK signaling pathway 1 1
dme04013 MAPK signaling pathway fly 1 1
sce04011 MAPK signaling pathway yeast 11 6
hsa04950 Maturity onset diabetes of the young 2 2
hsa05162 Measles 62 29
mmu05162 Measles 8 7
rno05162 Measles 2 2
ssc05162 Measles 1 1
sce04113 Meiosis yeast 19 14
spo04113 Meiosis yeast 1 1
hsa04916 Melanogenesis 17 11
bta04916 Melanogenesis 1 1
mmu04916 Melanogenesis 6 6
rno04916 Melanogenesis 1 1
xla04916 Melanogenesis 2 2
hsa05218 Melanoma 52 18
rno05218 Melanoma 1 1
mmu05218 Melanoma 1 1
hsa01100 Metabolic pathways 15 13
rno01100 Metabolic pathways 3 3
mmu01100 Metabolic pathways 3 3
ocu01100 Metabolic pathways 1 1
sce01100 Metabolic pathways 3 3
spo01100 Metabolic pathways 1 1
ssc01100 Metabolic pathways 1 1
hsa00980 Metabolism of xenobiotics by cytochrome P450 1 1
hsa05206 MicroRNAs in cancer 125 48
mmu05206 MicroRNAs in cancer 6 6
rno05206 MicroRNAs in cancer 4 1
rno04978 Mineral absorption 1 1
hsa04978 Mineral absorption 3 3
sce03430 Mismatch repair 6 6
hsa03430 Mismatch repair 5 5
spo03430 Mismatch repair 1 1
hsa05032 Morphine addiction 8 7
bta05032 Morphine addiction 2 2
mmu05032 Morphine addiction 3 3
rno05032 Morphine addiction 1 1
hsa03015 mRNA surveillance pathway 2 2
mmu03015 mRNA surveillance pathway 1 1
cel04150 mTOR signaling pathway 1 1
hsa04150 mTOR signaling pathway 23 12
mmu04150 mTOR signaling pathway 2 2
rno04150 mTOR signaling pathway 6 3
dme04150 mTOR signaling pathway 1 1
mmu04650 Natural killer cell mediated cytotoxicity 5 5
ssc04650 Natural killer cell mediated cytotoxicity 1 1
hsa04650 Natural killer cell mediated cytotoxicity 35 24
rno04650 Natural killer cell mediated cytotoxicity 1 1
hsa04080 Neuroactive ligand receptor interaction 22 18
rno04080 Neuroactive ligand receptor interaction 7 6
mmu04080 Neuroactive ligand receptor interaction 1 1
hsa04722 Neurotrophin signaling pathway 74 35
rno04722 Neurotrophin signaling pathway 6 3
mmu04722 Neurotrophin signaling pathway 5 5
hsa04064 NF kappa B signaling pathway 25 17
mmu04064 NF kappa B signaling pathway 5 5
rno04064 NF kappa B signaling pathway 2 2
sce00510 N Glycan biosynthesis 1 1
hsa00510 N Glycan biosynthesis 2 2
rno05033 Nicotine addiction 2 2
hsa05033 Nicotine addiction 2 1
hsa04621 NOD like receptor signaling pathway 16 8
mmu04621 NOD like receptor signaling pathway 1 1
ssc04621 NOD like receptor signaling pathway 1 1
dre04621 NOD like receptor signaling pathway 1 1
hsa04932 Non alcoholic fatty liver disease (NAFLD) 41 18
mmu04932 Non alcoholic fatty liver disease (NAFLD) 3 3
rno04932 Non alcoholic fatty liver disease (NAFLD) 5 2
hsa03450 Non homologous end joining 5 5
sce03450 Non homologous end joining 1 1
mmu03450 Non homologous end joining 1 1
hsa05223 Non small cell lung cancer 50 18
rno05223 Non small cell lung cancer 1 1
mmu05223 Non small cell lung cancer 2 2
dme04330 Notch signaling pathway 2 2
hsa04330 Notch signaling pathway 16 8
rno04330 Notch signaling pathway 1 1
sce03420 Nucleotide excision repair 6 6
hsa03420 Nucleotide excision repair 7 6
spo03420 Nucleotide excision repair 1 1
bta04740 Olfactory transduction 2 2
mmu04740 Olfactory transduction 3 3
hsa04740 Olfactory transduction 2 1
hsa04114 Oocyte meiosis 28 16
bta04114 Oocyte meiosis 1 1
mmu04114 Oocyte meiosis 3 3
xla04114 Oocyte meiosis 6 6
rno04114 Oocyte meiosis 1 1
hsa04380 Osteoclast differentiation 49 24
mmu04380 Osteoclast differentiation 9 9
ssc04380 Osteoclast differentiation 1 1
hsa00511 Other glycan degradation 1 1
bta04913 Ovarian steroidogenesis 1 1
hsa04913 Ovarian steroidogenesis 7 4
mmu04913 Ovarian steroidogenesis 1 1
rno04913 Ovarian steroidogenesis 1 1
hsa04921 Oxytocin signaling pathway 63 30
ssc04921 Oxytocin signaling pathway 1 1
mmu04921 Oxytocin signaling pathway 6 5
bta04921 Oxytocin signaling pathway 1 1
ocu04921 Oxytocin signaling pathway 1 1
rno04921 Oxytocin signaling pathway 4 4
hsa04115 p53 signaling pathway 42 13
xla04115 p53 signaling pathway 1 1
mmu04115 p53 signaling pathway 2 2
hsa05212 Pancreatic cancer 56 21
rno05212 Pancreatic cancer 2 2
mmu05212 Pancreatic cancer 1 1
rno04972 Pancreatic secretion 2 2
hsa04972 Pancreatic secretion 6 4
mmu04972 Pancreatic secretion 1 1
bta05012 Parkinson's disease 1 1
mmu05012 Parkinson's disease 1 1
hsa05012 Parkinson's disease 8 4
hsa05130 Pathogenic Escherichia coli infection 18 10
hsa05200 Pathways in cancer 174 72
rno05200 Pathways in cancer 4 4
bta05200 Pathways in cancer 1 1
mmu05200 Pathways in cancer 16 16
ssc05200 Pathways in cancer 1 1
hsa00040 Pentose and glucuronate interconversions 1 1
hsa04146 Peroxisome 7 5
sce04146 Peroxisome 3 2
ssc04146 Peroxisome 1 1
ath04146 Peroxisome 1 1
hsa05133 Pertussis 27 13
mmu05133 Pertussis 2 2
hsa04145 Phagosome 17 13
mmu04145 Phagosome 1 1
bta04145 Phagosome 1 1
cfa04145 Phagosome 1 1
dme04145 Phagosome 1 1
hsa04070 Phosphatidylinositol signaling system 8 5
rno04070 Phosphatidylinositol signaling system 2 2
bta04744 Phototransduction 4 4
hsa04744 Phototransduction 1 1
mmu04744 Phototransduction 2 2
dme04745 Phototransduction fly 1 1
hsa04151 PI3K Akt signaling pathway 139 65
rno04151 PI3K Akt signaling pathway 8 5
mmu04151 PI3K Akt signaling pathway 12 12
bta04151 PI3K Akt signaling pathway 1 1
ssc04151 PI3K Akt signaling pathway 1 1
sly04075 Plant hormone signal transduction 2 2
ath04075 Plant hormone signal transduction 27 27
hsa04611 Platelet activation 33 19
bta04611 Platelet activation 1 1
mmu04611 Platelet activation 5 5
rno04611 Platelet activation 3 3
hsa00860 Porphyrin and chlorophyll metabolism 1 1
hsa03320 PPAR signaling pathway 2 2
mmu03320 PPAR signaling pathway 1 1
hsa00120 Primary bile acid biosynthesis 2 2
ssc00120 Primary bile acid biosynthesis 1 1
hsa05340 Primary immunodeficiency 17 12
mmu05340 Primary immunodeficiency 4 4
rno05340 Primary immunodeficiency 1 1
bta05020 Prion diseases 1 1
hsa05020 Prion diseases 19 12
mmu05020 Prion diseases 2 2
bta04914 Progesterone mediated oocyte maturation 1 1
hsa04914 Progesterone mediated oocyte maturation 27 16
mmu04914 Progesterone mediated oocyte maturation 3 3
xla04914 Progesterone mediated oocyte maturation 2 2
rno04914 Progesterone mediated oocyte maturation 1 1
dre04914 Progesterone mediated oocyte maturation 1 1
mmu04917 Prolactin signaling pathway 5 5
hsa04917 Prolactin signaling pathway 34 18
rno04917 Prolactin signaling pathway 1 1
hsa00640 Propanoate metabolism 1 1
hsa05215 Prostate cancer 85 31
rno05215 Prostate cancer 1 1
mmu05215 Prostate cancer 6 6
ssc05215 Prostate cancer 1 1
rno04974 Protein digestion and absorption 1 1
hsa04974 Protein digestion and absorption 1 1
hsa03060 Protein export 2 2
spo03060 Protein export 1 1
cfa03060 Protein export 1 1
hsa04141 Protein processing in endoplasmic reticulum 18 15
mmu04141 Protein processing in endoplasmic reticulum 5 4
rno04141 Protein processing in endoplasmic reticulum 1 1
sce04141 Protein processing in endoplasmic reticulum 1 1
spo04141 Protein processing in endoplasmic reticulum 1 1
cfa04141 Protein processing in endoplasmic reticulum 1 1
ssc04141 Protein processing in endoplasmic reticulum 2 2
dme04141 Protein processing in endoplasmic reticulum 1 1
dre04141 Protein processing in endoplasmic reticulum 1 1
hsa05205 Proteoglycans in cancer 104 48
bta05205 Proteoglycans in cancer 1 1
mmu05205 Proteoglycans in cancer 9 9
rno05205 Proteoglycans in cancer 4 4
rno04964 Proximal tubule bicarbonate reclamation 1 1
hsa00230 Purine metabolism 3 3
sce00230 Purine metabolism 2 2
spo00230 Purine metabolism 1 1
rno00230 Purine metabolism 1 1
spo00240 Pyrimidine metabolism 1 1
sce00240 Pyrimidine metabolism 1 1
hsa00240 Pyrimidine metabolism 1 1
sce00620 Pyruvate metabolism 1 1
hsa00620 Pyruvate metabolism 1 1
hsa04015 Rap1 signaling pathway 52 29
mmu04015 Rap1 signaling pathway 3 3
rno04015 Rap1 signaling pathway 4 4
hsa04014 Ras signaling pathway 53 28
rno04014 Ras signaling pathway 3 3
mmu04014 Ras signaling pathway 7 6
bta04014 Ras signaling pathway 1 1
hsa04810 Regulation of actin cytoskeleton 68 35
gga04810 Regulation of actin cytoskeleton 5 4
mmu04810 Regulation of actin cytoskeleton 4 4
rno04810 Regulation of actin cytoskeleton 4 4
xla04810 Regulation of actin cytoskeleton 1 1
pfa04140 Regulation of autophagy 1 1
hsa04140 Regulation of autophagy 5 5
sce04140 Regulation of autophagy 1 1
dme04140 Regulation of autophagy 1 1
bta04923 Regulation of lipolysis in adipocytes 1 1
mmu04923 Regulation of lipolysis in adipocytes 1 1
hsa04923 Regulation of lipolysis in adipocytes 14 7
rno04923 Regulation of lipolysis in adipocytes 5 2
hsa05211 Renal cell carcinoma 34 18
mmu05211 Renal cell carcinoma 2 2
rno05211 Renal cell carcinoma 2 2
mmu04614 Renin angiotensin system 1 1
hsa04614 Renin angiotensin system 2 2
rno04614 Renin angiotensin system 1 1
bta04924 Renin secretion 1 1
mmu04924 Renin secretion 2 2
hsa04924 Renin secretion 10 9
ocu04924 Renin secretion 1 1
rno04924 Renin secretion 1 1
hsa00830 Retinol metabolism 1 1
bta04723 Retrograde endocannabinoid signaling 1 1
mmu04723 Retrograde endocannabinoid signaling 1 1
hsa04723 Retrograde endocannabinoid signaling 8 7
ocu04723 Retrograde endocannabinoid signaling 1 1
rno04723 Retrograde endocannabinoid signaling 8 7
hsa05323 Rheumatoid arthritis 15 7
mmu05323 Rheumatoid arthritis 3 3
mmu00740 Riboflavin metabolism 1 1
sce03010 Ribosome 1 1
hsa03010 Ribosome 1 1
hsa04622 RIG I like receptor signaling pathway 16 10
sce03018 RNA degradation 5 4
hsa03018 RNA degradation 9 7
mmu03018 RNA degradation 1 1
ago03018 RNA degradation 1 1
spo03018 RNA degradation 2 2
hsa03013 RNA transport 18 13
sce03013 RNA transport 3 3
mmu03013 RNA transport 1 1
spo03013 RNA transport 1 1
rno03013 RNA transport 1 1
bta04970 Salivary secretion 1 1
mmu04970 Salivary secretion 2 2
rno04970 Salivary secretion 2 2
hsa04970 Salivary secretion 6 5
hsa05132 Salmonella infection 29 13
mmu05132 Salmonella infection 4 4
gga05132 Salmonella infection 3 1
rno05132 Salmonella infection 1 1
bta04726 Serotonergic synapse 1 1
hsa04726 Serotonergic synapse 17 12
mmu04726 Serotonergic synapse 2 2
rno04726 Serotonergic synapse 2 2
ocu04726 Serotonergic synapse 1 1
hsa05131 Shigellosis 31 16
hsa04550 Signaling pathways regulating pluripotency of stem cells 41 17
rno04550 Signaling pathways regulating pluripotency of stem cells 1 1
mmu04550 Signaling pathways regulating pluripotency of stem cells 8 6
hsa05222 Small cell lung cancer 71 23
mmu05222 Small cell lung cancer 3 3
rno00600 Sphingolipid metabolism 1 1
hsa04071 Sphingolipid signaling pathway 38 18
rno04071 Sphingolipid signaling pathway 2 2
mmu04071 Sphingolipid signaling pathway 1 1
hsa03040 Spliceosome 6 5
rno03040 Spliceosome 1 1
mmu03040 Spliceosome 2 2
ssc03040 Spliceosome 1 1
spu03040 Spliceosome 1 1
dme03040 Spliceosome 1 1
hsa05150 Staphylococcus aureus infection 5 5
ocu00500 Starch and sucrose metabolism 1 1
hsa00500 Starch and sucrose metabolism 1 1
hsa00100 Steroid biosynthesis 1 1
hsa00140 Steroid hormone biosynthesis 1 1
hsa04721 Synaptic vesicle cycle 5 5
rno04721 Synaptic vesicle cycle 2 2
hsa05322 Systemic lupus erythematosus 12 10
mmu05322 Systemic lupus erythematosus 2 2
bta04742 Taste transduction 1 1
mmu04742 Taste transduction 1 1
hsa04742 Taste transduction 5 4
rno04742 Taste transduction 2 2
hsa04660 T cell receptor signaling pathway 60 33
mmu04660 T cell receptor signaling pathway 11 10
ssc04660 T cell receptor signaling pathway 1 1
rno04660 T cell receptor signaling pathway 3 3
hsa00900 Terpenoid backbone biosynthesis 1 1
hsa04350 TGF beta signaling pathway 21 12
rno04350 TGF beta signaling pathway 1 1
hsa05216 Thyroid cancer 30 10
mmu05216 Thyroid cancer 4 4
rno04919 Thyroid hormone signaling pathway 3 3
hsa04919 Thyroid hormone signaling pathway 66 24
bta04919 Thyroid hormone signaling pathway 2 2
mmu04919 Thyroid hormone signaling pathway 5 5
hsa04918 Thyroid hormone synthesis 8 7
bta04918 Thyroid hormone synthesis 1 1
mmu04918 Thyroid hormone synthesis 1 1
rno04918 Thyroid hormone synthesis 2 2
ssc04918 Thyroid hormone synthesis 1 1
gga04530 Tight junction 1 1
hsa04530 Tight junction 25 14
mmu04530 Tight junction 1 1
rno04530 Tight junction 4 3
hsa04668 TNF signaling pathway 35 18
rno04668 TNF signaling pathway 1 1
mmu04668 TNF signaling pathway 3 3
hsa04620 Toll like receptor signaling pathway 39 19
mmu04620 Toll like receptor signaling pathway 3 3
rno04620 Toll like receptor signaling pathway 1 1
gga04620 Toll like receptor signaling pathway 3 1
bta04620 Toll like receptor signaling pathway 1 1
xla04620 Toll like receptor signaling pathway 1 1
hsa05145 Toxoplasmosis 33 21
rno05145 Toxoplasmosis 2 2
mmu05145 Toxoplasmosis 2 2
ssc05145 Toxoplasmosis 1 1
hsa05202 Transcriptional misregulation in cancer 92 40
mmu05202 Transcriptional misregulation in cancer 4 4
hsa00380 Tryptophan metabolism 1 1
hsa05152 Tuberculosis 39 22
rno05152 Tuberculosis 2 2
mmu05152 Tuberculosis 2 1
hsa04940 Type I diabetes mellitus 3 3
hsa04930 Type II diabetes mellitus 16 10
mmu04930 Type II diabetes mellitus 1 1
ocu04930 Type II diabetes mellitus 1 1
rno04930 Type II diabetes mellitus 5 2
mmu00350 Tyrosine metabolism 1 1
spo04120 Ubiquitin mediated proteolysis 3 3
hsa04120 Ubiquitin mediated proteolysis 28 14
sce04120 Ubiquitin mediated proteolysis 5 2
dme04120 Ubiquitin mediated proteolysis 2 2
ath04120 Ubiquitin mediated proteolysis 5 5
xla04120 Ubiquitin mediated proteolysis 1 1
sce00513 Various types of N glycan biosynthesis 1 1
hsa04270 Vascular smooth muscle contraction 16 12
bta04270 Vascular smooth muscle contraction 1 1
mmu04270 Vascular smooth muscle contraction 1 1
ocu04270 Vascular smooth muscle contraction 1 1
rno04270 Vascular smooth muscle contraction 2 2
xla04270 Vascular smooth muscle contraction 1 1
gga04270 Vascular smooth muscle contraction 2 1
hsa04962 Vasopressin regulated water reabsorption 7 6
mmu04962 Vasopressin regulated water reabsorption 2 2
bta04962 Vasopressin regulated water reabsorption 1 1
rno04370 VEGF signaling pathway 3 3
gga04370 VEGF signaling pathway 2 2
hsa04370 VEGF signaling pathway 31 15
mmu04370 VEGF signaling pathway 1 1
xla04370 VEGF signaling pathway 1 1
vch05110 Vibrio cholerae infection 1 1
hsa05110 Vibrio cholerae infection 6 3
vch05111 Vibrio cholerae pathogenic cycle 1 1
hsa05203 Viral carcinogenesis 103 41
rno05203 Viral carcinogenesis 4 4
bta05203 Viral carcinogenesis 1 1
mmu05203 Viral carcinogenesis 7 7
hsa05416 Viral myocarditis 16 8
mmu05416 Viral myocarditis 4 4
hsa04310 Wnt signaling pathway 63 18
gga04310 Wnt signaling pathway 4 2
rno04310 Wnt signaling pathway 1 1
ssc04310 Wnt signaling pathway 1 1
bta04310 Wnt signaling pathway 1 1
mmu04310 Wnt signaling pathway 6 6
dre04310 Wnt signaling pathway 1 1
xla04310 Wnt signaling pathway 2 2
Links redirect to the KEGG database with a color overlay corresponding to ELM classes.

Coloring is as follows:
CLV (cleavage site)
DOC (docking site)
DEG (degradation motif)
LIG (ligand binding motif)
MOD (modification site)
TRG (targeting motif)
multiple classes per sequence
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
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