The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002573 Q13480-2 GAB1
GAB1_HUMAN
447 450 SSEELDENYVPMNPNSPPRQ TP --- Homo sapiens (Human) 724

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Lehr,2000 support likely
experimental MI:0039 edman degradation in vitro Lehr,2000 support likely ParticipantIdentification
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Lehr,2000 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lehr,2000 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P27986) P85A_HUMAN PF00017 (SH2)
SH2 domain
[mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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